Everyone assumes that stacking buffers beats taking just one. In a crossover trial of ten highly trained female CrossFit athletes, sodium bicarbonate cut 6-km time trial time by 21.5 seconds versus placebo, while sodium citrate and the combo weren't clearly better than placebo. Bicarbonate also beat citrate by 11.6 seconds and the combination by 17.2 seconds. The catch was more pre-exercise stomach discomfort. Here is what the study found, why the stack flopped, and how to trial it safely.
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